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Systemic Issues & Complications

Body Response to Injury & Surgery

The metabolic response to injury: homeostasis, the graded nature of the response, the biphasic neuroendocrine reaction, and how the body behaves in the first 24 to 48 hours after surgical injury.

What this lecture covers

  • Basic concepts in homeostasis
  • The graded nature of the injury response
  • The biphasic neuroendocrine response
  • The integrated response to surgical injury in the first 24–48 hours
  • Systemic inflammatory response syndrome
  • The counter-regulatory hormone response
  • Physiological and metabolic consequences
  • Modifying the response
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